Metamorphopsia severity acts as a predictor of impaired VRQoL, over and above decrements due to reduced vision. Physician assessment of symptoms underestimated the self-reported presence of metamorphopsia. Metamorphopsia was highly prevalent in patients with VMT and associated with significantly lower VRQoL. The adjusted model showed that metamorphopsia severity and age were significantly associated with lower VFQ-25 scores. The largest difference in VFQ-25 scores was observed for near activities (metamorphopsia: 75.3, No metamorphopsia: 90.2). 91.4), and mean VA (LogMAR) was worse (0.44 vs. without metamorphopsia, the VFQ-25 composite score was lower (82.3 vs. Physician assessment of metamorphopsia was 53.0% (95% CI: 45.5–60.3%). ![]() The prevalence of self-reported metamorphopsia was 69.7% (95% CI 62.6–76.3%) and was higher in eyes with a concomitant FTMH vs. Predictors of VRQoL were assessed using ordinary-least-squares regression adjusting for clinically important variables. ANOVA and predicted least-squares means were used to estimate the impact of metamorphopsia on VRQoL. Physicians recorded clinical and ocular characteristics in both eyes including a physician assessment of metamorphopsia. VRQoL was assessed using the Visual Function Questionnaire (VFQ-25). Self-reported metamorphopsia was determined using the metamorphopsia questionnaire. Patients and methodsĪ prospective, cross-sectional multi-centre study in the United Kingdom of 185 patients with VMT, with or without a full thickness macular hole (FTMH). To report the prevalence and severity of metamorphopsia, estimate its impact on vision-related quality of life (VRQoL) and evaluate predictors of VRQoL in patients with vitreomacular traction (VMT).
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